Creative Biolabs

About Creative Biolabs

Creative Biolabs key features

• Diverse Discovery Technologies: Offers various binder discovery methods including phage display, yeast display, hybridoma, and single B cell sorting, tailored for different applications and targets.
• Comprehensive Characterization Services: Provides binding analysis, sequence analysis, immunogenicity assessment, and functional analysis to ensure the quality and specificity of antibodies.
• Advanced Engineering Capabilities: Includes antibody conversion (humanization, camelization), property optimization (affinity maturation, stability improvement), and labeling/conjugation services.
• Custom Production and Manufacturing: Facilitates custom production of membrane proteins, virus-like particles, and recombinant antibodies, along with manufacturability assessments.
• Extensive Resource Library: Features peer-reviewed publications, FAQs, and knowledge hubs to support clients in understanding and utilizing the services effectively.

Creative Biolabs use cases

• Phage Display Library Construction: Creation of custom libraries for antibodies, peptides, and scaffolds to identify high-affinity binders for therapeutic and diagnostic applications.
• Antibody Discovery: Utilization of various display technologies (e.g., phage, yeast) to discover monoclonal, polyclonal, and single-domain antibodies against specific targets.
• Post-Translational Modification Specific Antibody Discovery: Development of antibodies that specifically recognize post-translational modifications such as phosphorylation and ubiquitination.
• Custom Production of Membrane Proteins: Preparation and quality control of membrane proteins, including GPCRs and ion channels, for research and therapeutic use.
• Immunogenicity Analysis: Assessment of the immunogenic potential of antibodies and other proteins through in silico, ex vivo, and in vivo methods.

Useful for

• High Throughput Screening: The application allows for rapid identification of high-affinity binders from large libraries, significantly accelerating the discovery process for therapeutic and diagnostic applications.
• Diverse Library Options: It offers a variety of library types, including immune, naïve, and synthetic libraries, enabling tailored solutions for different research needs.
• Customizable Screening Strategies: The service provides tailored biopanning strategies to enhance the selection of specific binders, ensuring high specificity and affinity.
• Broad Target Compatibility: It supports screening against various target types, including purified proteins, intact cells, and complex biological samples, making it versatile for different research contexts.
• Expertise and Advanced Technology: The application leverages over 20 years of experience and cutting-edge technologies, ensuring reliable and efficient results in antibody and peptide discovery.

Price

• Premade Library Licensing: Options include Premade Antibody Library, Premade Peptide Library, Premade SdAb Library, and Immune Human Antibody Library.
• Premade Library Screening: Services for screening Premade Antibody Libraries, Premade Single Domain Antibody Libraries, and Premade Peptide Libraries.
• Custom Production Services: Includes Membrane Protein Preparation, Virus-Like Particle (VLP) Production, Recombinant Antibody Production, and Ascites Fluid based Antibody Production.
• Antibody Engineering Services: Services include Humanization, Camelization, Caninization, Simianization, Murinization, Chimeric Antibody Conversion, and ScFv/Fab Conversion.
• Characterization Services: Includes Affinity Measurement, Epitope Mapping, Immunogenicity Assessment, and Functional Analysis.