Profluent BioProfluent is committed to advancing innovation and development in the gene editing community, to bring new treatments to patients with major unmet needs. Under the OpenCRISPR initiative, we are releasing the world’s first open-source, AI-generated gene editor. With this launch, Profluent demonstrates the first successful precision editing of the human genome with customizable gene editors designed from scratch with AI. Through the OpenCRISPR training process, Profluent’s large language models (LLMs) learned from a massive scale of protein sequences overlaid with biological context to generate millions of diverse CRISPR-like proteins that do not occur in nature, thereby exponentially expanding virtually all known CRISPR families. We have decided to launch OpenCRISPR-1 (one of our AI-created gene editors) as an initial open-source release, making it freely available to license for ethical research and commercial uses. OpenCRISPR-1 maintains the prototypical architecture of a Type II Cas9 nuclease but is >400 mutations away from SpCas9 and nearly 200 mutations away from any other known natural CRISPR-associated protein. We also used our LLMs to generate a synthetic guide RNA that could be assembled with OpenCRISPR-1.
View Profluent Bio
Freed AIFreed is an AI tool specifically designed for clinicians in the medical field. It acts as a virtual medical scribe, significantly reducing documentation time while ensuring accurate results. With the help of Freed, clinicians can streamline their workload and enhance efficiency by focusing less on administrative tasks. The tool transcribes patient visits, extracting and summarizing medically relevant information in the appropriate format, similar to a human scribe. This allows clinicians to quickly generate SOAP notes, which are generated based on medical guidelines and best practice templates. Clinicians can review, edit, and copy the note into their preferred Electronic Health Record (EHR) with just one click. Freed is HIPAA compliant and prioritizes data privacy by not storing patient recordings. It offers a free trial for users to experience the benefits firsthand, and there are different pricing options available for individuals and groups. Overall, Freed aims to alleviate the burden of documentation for clinicians, enabling them to focus on patient care and ultimately reduce burnout.