PlanfitPlanfit is a free AI-powered fitness app primarily designed for gym beginners. It offers personalized workout plans generated by an AI trainer named 'Max'. The app creates individualized workouts tailored to users' goals, strength level, training ability, past workouts, and available gym equipment. It adapts over time by optimizing sets, reps, and weights with each user's workout. Planfit also provides detailed exercise guides, including clear video instructions, useful trainer tips, correct forms, and even breathing techniques. A distinct feature of the app is its ability to calculate and display progress visually so users can closely monitor their muscle recovery, exercise achievements, and workout balance. Max, the AI trainer, provides ongoing motivation and guidance throughout the user's fitness journey. Planfit also offers the functionality to view and share workout results. The targeted exercises, intuitive performance tracking, and personalized training provided by the Planfit app can contribute to an effective and balanced fitness routine.
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Profluent BioProfluent is committed to advancing innovation and development in the gene editing community, to bring new treatments to patients with major unmet needs. Under the OpenCRISPR initiative, we are releasing the world’s first open-source, AI-generated gene editor. With this launch, Profluent demonstrates the first successful precision editing of the human genome with customizable gene editors designed from scratch with AI. Through the OpenCRISPR training process, Profluent’s large language models (LLMs) learned from a massive scale of protein sequences overlaid with biological context to generate millions of diverse CRISPR-like proteins that do not occur in nature, thereby exponentially expanding virtually all known CRISPR families. We have decided to launch OpenCRISPR-1 (one of our AI-created gene editors) as an initial open-source release, making it freely available to license for ethical research and commercial uses. OpenCRISPR-1 maintains the prototypical architecture of a Type II Cas9 nuclease but is >400 mutations away from SpCas9 and nearly 200 mutations away from any other known natural CRISPR-associated protein. We also used our LLMs to generate a synthetic guide RNA that could be assembled with OpenCRISPR-1.